Monotreme glucagon-like peptide-1 in venom and gut: one gene - two very different functions.

Tsend-Ayush, Enkhjargal; He, Chuan; Myers, Mark A; Andrikopoulos, Sof; Wong, Nicole; Sexton, Patrick M; Wootten, Denise; Forbes, Briony E; Grutzner, Frank

Tsend-Ayush, Enkhjargal; He, Chuan; Myers, Mark A; Andrikopoulos, Sof; Wong, Nicole; Sexton, Patrick M; Wootten, Denise; Forbes, Briony E; Grutzner, Frank.

Afiliação

Tsend-Ayush E; Robinson Research Institute, School of Biological Sciences, The University of Adelaide, South Australia, 5000, Australia.
He C; Robinson Research Institute, School of Biological Sciences, The University of Adelaide, South Australia, 5000, Australia.
Myers MA; School of Applied and Biomedical Sciences, Federation University Australia, Mount Helen, Victoria, 3353, Australia.
Andrikopoulos S; Department of Medicine, Austin Health, The University of Melbourne, Heidelberg, Victoria 3084, Australia.
Wong N; Department of Medicine, Austin Health, The University of Melbourne, Heidelberg, Victoria 3084, Australia.
Sexton PM; Monash Institute of Pharmaceutical Sciences and Department of Pharmacology, Monash University, Parkville, Victoria, 3052, Australia.
Wootten D; Monash Institute of Pharmaceutical Sciences and Department of Pharmacology, Monash University, Parkville, Victoria, 3052, Australia.
Forbes BE; Robinson Research Institute, School of Biological Sciences, The University of Adelaide, South Australia, 5000, Australia.
Grutzner F; School of Medicine, Flinders University, Bedford Park, South Australia, 5042, Australia.

Sci Rep ; 6: 37744, 2016 11 29.

Article em En | MEDLINE | ID: mdl-27898108

Assuntos

Peptídeo 1 Semelhante ao Glucagon/genética; Mucosa Intestinal/metabolismo; Monotremados; Ornitorrinco; Tachyglossidae; Peçonhas/genética; Peçonhas/metabolismo; Animais; Evolução Biológica; Células Cultivadas; Exenatida; Peptídeo 1 Semelhante ao Glucagon/metabolismo; Incretinas/metabolismo; Insulina/metabolismo; Secreção de Insulina; Peptídeos/genética; Filogenia; Seleção Genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ornitorrinco / Peçonhas / Tachyglossidae / Peptídeo 1 Semelhante ao Glucagon / Mucosa Intestinal / Monotremados Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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