New treatment strategy with nuclear factor-&#954;B inhibitor for pancreatic cancer.

Horiuchi, Takashi; Uwagawa, Tadashi; Shirai, Yoshihiro; Saito, Nobuhiro; Iwase, Ryota; Haruki, Koichiro; Shiba, Hiroaki; Ohashi, Toya; Yanaga, Katsuhiko

New treatment strategy with nuclear factor-κB inhibitor for pancreatic cancer.

Horiuchi, Takashi; Uwagawa, Tadashi; Shirai, Yoshihiro; Saito, Nobuhiro; Iwase, Ryota; Haruki, Koichiro; Shiba, Hiroaki; Ohashi, Toya; Yanaga, Katsuhiko.

Afiliação

Horiuchi T; Department of Surgery, The Jikei University School of Medicine, Tokyo, Japan. Electronic address: horiuchi@jikei.ac.jp.
Uwagawa T; Department of Surgery, The Jikei University School of Medicine, Tokyo, Japan.
Shirai Y; Department of Surgery, The Jikei University School of Medicine, Tokyo, Japan.
Saito N; Department of Surgery, The Jikei University School of Medicine, Tokyo, Japan.
Iwase R; Department of Surgery, The Jikei University School of Medicine, Tokyo, Japan.
Haruki K; Department of Surgery, The Jikei University School of Medicine, Tokyo, Japan.
Shiba H; Department of Surgery, The Jikei University School of Medicine, Tokyo, Japan.
Ohashi T; Division of Gene Therapy, Research Center for Medical Science, The Jikei University School of Medicine, Tokyo, Japan.
Yanaga K; Department of Surgery, The Jikei University School of Medicine, Tokyo, Japan.

J Surg Res ; 206(1): 1-8, 2016 11.

Article em En | MEDLINE | ID: mdl-27916347

Assuntos

Albuminas/uso terapêutico; Antineoplásicos/uso terapêutico; Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico; Carcinoma Ductal Pancreático/tratamento farmacológico; Desoxicitidina/análogos & derivados; Guanidinas/uso terapêutico; Paclitaxel/uso terapêutico; Neoplasias Pancreáticas/tratamento farmacológico; Albuminas/farmacologia; Animais; Antineoplásicos/farmacologia; Protocolos de Quimioterapia Combinada Antineoplásica/farmacologia; Apoptose/efeitos dos fármacos; Benzamidinas; Biomarcadores/metabolismo; Carcinoma Ductal Pancreático/metabolismo; Linhagem Celular Tumoral; Desoxicitidina/farmacologia; Desoxicitidina/uso terapêutico; Esquema de Medicação; Guanidinas/farmacologia; Humanos; Injeções Intraperitoneais; Injeções Intravenosas; Masculino; Camundongos; Camundongos Endogâmicos BALB C; NF-kappa B/antagonistas & inibidores; Paclitaxel/farmacologia; Neoplasias Pancreáticas/metabolismo; Ensaios Antitumorais Modelo de Xenoenxerto; Gencitabina

Palavras-chave

Gemcitabine; NF-κB; Nab-paclitaxel; Nafamostat mesilate; Orthotopic mouse model; Pancreatic cancer

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Protocolos de Quimioterapia Combinada Antineoplásica / Paclitaxel / Carcinoma Ductal Pancreático / Desoxicitidina / Albuminas / Guanidinas / Antineoplásicos Tipo de estudo: Guideline / Prognostic_studies / Screening_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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