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Anti-MOG (Myelin Oligodendrocyte Glycoprotein)-Positive Severe Optic Neuritis with Optic Disc Ischaemia and Macular Star.
Moura, Frederico Castelo; Sato, Douglas Kazutoshi; Rimkus, Carolina Medeiros; Apóstolos-Pereira, Samira Luisa; de Oliveira, Luana Michelli; Leite, Claudia Costa; Fujihara, Kazuo; Monteiro, Mario Luiz Ribeiro; Callegaro, Dagoberto.
Afiliação
  • Moura FC; Department of Ophthalmology, Faculty of Medicine, University of Sao Paulo , Sao Paulo, Brazil.
  • Sato DK; Department of Neurology, Faculty of Medicine, University of Sao Paulo, Sao Paulo, Brazil, ; Department of Multiple Sclerosis Therapeutics, Tohoku University Graduate School of Medicine, Sendai, Japan, and.
  • Rimkus CM; Department of Radiology and Oncology, Faculty of Medicine, University of Sao Paulo , Sao Paulo, Brazil.
  • Apóstolos-Pereira SL; Department of Neurology, Faculty of Medicine, University of Sao Paulo , Sao Paulo, Brazil.
  • de Oliveira LM; Department of Neurology, Faculty of Medicine, University of Sao Paulo , Sao Paulo, Brazil.
  • Leite CC; Department of Radiology and Oncology, Faculty of Medicine, University of Sao Paulo , Sao Paulo, Brazil.
  • Fujihara K; Department of Multiple Sclerosis Therapeutics, Tohoku University Graduate School of Medicine , Sendai, Japan , and.
  • Monteiro ML; Department of Ophthalmology, Faculty of Medicine, University of Sao Paulo , Sao Paulo, Brazil.
  • Callegaro D; Department of Neurology, Faculty of Medicine, University of Sao Paulo , Sao Paulo, Brazil.
Neuroophthalmology ; 39(6): 285-288, 2015 Dec.
Article em En | MEDLINE | ID: mdl-27928371
A 44-year-old man presented with severe right visual loss. The right fundus examination showed marked optic disc oedema associated with partial macular star. Serological blood tests for infectious agents were all negative. Serum aquaporin-4 antibody was negative but anti-MOG (myelin oligodendrocyte glycoprotein) was positive. Magnetic resonance revealed extensive lesion in right optic nerve. There was no visual improvement after intravenous therapy. Patient had no further attacks after follow-up. Optic disc oedema with macular star is found in several infectious and non-inflammatory disorders, but it has not been reported in optic neuritis (ON) associated with autoantibodies to myelin oligodendrocyte glycoprotein (anti-MOG).
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2015 Tipo de documento: Article