BIX01294, an inhibitor of histone methyltransferase, induces autophagy-dependent differentiation of glioma stem-like cells.

Ciechomska, Iwona Anna; Przanowski, Piotr; Jackl, Judyta; Wojtas, Bartosz; Kaminska, Bozena

Ciechomska, Iwona Anna; Przanowski, Piotr; Jackl, Judyta; Wojtas, Bartosz; Kaminska, Bozena.

Afiliação

Ciechomska IA; Laboratory of Molecular Neurobiology, Neurobiology Center, Nencki Institute of Experimental Biology of Polish Academy of Science, 3 Pasteur Str., 02-093 Warsaw, Poland.
Przanowski P; Laboratory of Molecular Neurobiology, Neurobiology Center, Nencki Institute of Experimental Biology of Polish Academy of Science, 3 Pasteur Str., 02-093 Warsaw, Poland.
Jackl J; Laboratory of Molecular Neurobiology, Neurobiology Center, Nencki Institute of Experimental Biology of Polish Academy of Science, 3 Pasteur Str., 02-093 Warsaw, Poland.
Wojtas B; Laboratory of Molecular Neurobiology, Neurobiology Center, Nencki Institute of Experimental Biology of Polish Academy of Science, 3 Pasteur Str., 02-093 Warsaw, Poland.
Kaminska B; Laboratory of Molecular Neurobiology, Neurobiology Center, Nencki Institute of Experimental Biology of Polish Academy of Science, 3 Pasteur Str., 02-093 Warsaw, Poland.

Sci Rep ; 6: 38723, 2016 12 09.

Article em En | MEDLINE | ID: mdl-27934912

Assuntos

Autofagia/efeitos dos fármacos; Azepinas/farmacologia; Neoplasias Encefálicas/patologia; Diferenciação Celular/efeitos dos fármacos; Inibidores Enzimáticos/farmacologia; Glioblastoma/patologia; Histona-Lisina N-Metiltransferase/antagonistas & inibidores; Histonas/antagonistas & inibidores; Células-Tronco Neoplásicas/patologia; Quinazolinas/farmacologia; Relação Dose-Resposta a Droga; Histona Metiltransferases; Humanos; Células Tumorais Cultivadas

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quinazolinas / Autofagia / Azepinas / Células-Tronco Neoplásicas / Neoplasias Encefálicas / Histonas / Diferenciação Celular / Histona-Lisina N-Metiltransferase / Glioblastoma / Inibidores Enzimáticos Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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