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Trehalose-6-Phosphate-Mediated Toxicity Determines Essentiality of OtsB2 in Mycobacterium tuberculosis In Vitro and in Mice.
Korte, Jan; Alber, Marina; Trujillo, Carolina M; Syson, Karl; Koliwer-Brandl, Hendrik; Deenen, René; Köhrer, Karl; DeJesus, Michael A; Hartman, Travis; Jacobs, William R; Bornemann, Stephen; Ioerger, Thomas R; Ehrt, Sabine; Kalscheuer, Rainer.
Afiliação
  • Korte J; Institute for Pharmaceutical Biology and Biotechnology, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
  • Alber M; Institute for Medical Microbiology and Hospital Hygiene, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
  • Trujillo CM; Institute for Medical Microbiology and Hospital Hygiene, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
  • Syson K; Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America.
  • Koliwer-Brandl H; Department of Biological Chemistry, John Innes Centre, Norwich Research Park, Norwich, Norfolk, United Kingdom.
  • Deenen R; Institute for Medical Microbiology and Hospital Hygiene, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
  • Köhrer K; Biological and Medical Research Center (BMFZ), Cluster of Excellence on Plant Sciences (CEPLAS), Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
  • DeJesus MA; Biological and Medical Research Center (BMFZ), Cluster of Excellence on Plant Sciences (CEPLAS), Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
  • Hartman T; Department of Computer Science, Texas A&M University, College Station, Texas, United States of America.
  • Jacobs WR; Department of Microbiology and Immunology, Howard Hughes Medical Institute, Albert Einstein College of Medicine, Bronx, New York, United States of America.
  • Bornemann S; Department of Microbiology and Immunology, Howard Hughes Medical Institute, Albert Einstein College of Medicine, Bronx, New York, United States of America.
  • Ioerger TR; Department of Biological Chemistry, John Innes Centre, Norwich Research Park, Norwich, Norfolk, United Kingdom.
  • Ehrt S; Department of Computer Science, Texas A&M University, College Station, Texas, United States of America.
  • Kalscheuer R; Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America.
PLoS Pathog ; 12(12): e1006043, 2016 Dec.
Article em En | MEDLINE | ID: mdl-27936238
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fosfatos Açúcares / Proteínas de Bactérias / Trealose / Tuberculose / Monoéster Fosfórico Hidrolases / Mycobacterium tuberculosis Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fosfatos Açúcares / Proteínas de Bactérias / Trealose / Tuberculose / Monoéster Fosfórico Hidrolases / Mycobacterium tuberculosis Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article