The effect of smoking on the frequencies of asymmetrical and symmetrical chromosome exchanges in human lymphocytes.
Mutat Res
; 224(2): 151-6, 1989 Oct.
Article
em En
| MEDLINE
| ID: mdl-2797034
ABSTRACT
Cytogenetic analysis was performed on blood lymphocyte cultures from 12 moderate smokers (15-20 cigarettes/day) and 12 non-smokers. An increase in dicentrics was observed in the smokers using block-stained material but this was not significant. Analysis of banded material, enabling both symmetrical and asymmetrical aberrations to be scored, revealed a significant increase in total aberrations thus emphasizing the need to identify all chromosome rearrangements when examining the effects of low-level chronic exposures to clastogens.
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Base de dados:
MEDLINE
Assunto principal:
Plantas Tóxicas
/
Nicotiana
/
Linfócitos
/
Fumar
/
Aberrações Cromossômicas
Tipo de estudo:
Prognostic_studies
Limite:
Adult
/
Humans
/
Middle aged
Idioma:
En
Ano de publicação:
1989
Tipo de documento:
Article