mir-218-2 promotes glioblastomas growth, invasion and drug resistance by targeting CDC27.

Feng, Zhuoying; Zhang, Luping; Zhou, Junchen; Zhou, Shuai; Li, Li; Guo, Xuyan; Feng, Guoying; Ma, Ze; Huang, Wenhua; Huang, Fei

Feng, Zhuoying; Zhang, Luping; Zhou, Junchen; Zhou, Shuai; Li, Li; Guo, Xuyan; Feng, Guoying; Ma, Ze; Huang, Wenhua; Huang, Fei.

Afiliação

Feng Z; Institute of Human Anatomy and Histology and Embryology, Otology & Neuroscience Center, Binzhou Medical University, Laishan District, Shandong Province, 264003,China.
Zhang L; Institute of Human Anatomy and Histology and Embryology, Otology & Neuroscience Center, Binzhou Medical University, Laishan District, Shandong Province, 264003,China.
Zhou J; Institute of Human Anatomy and Histology and Embryology, Otology & Neuroscience Center, Binzhou Medical University, Laishan District, Shandong Province, 264003,China.
Zhou S; Institute of Human Anatomy and Histology and Embryology, Otology & Neuroscience Center, Binzhou Medical University, Laishan District, Shandong Province, 264003,China.
Li L; Institute of Human Anatomy and Histology and Embryology, Otology & Neuroscience Center, Binzhou Medical University, Laishan District, Shandong Province, 264003,China.
Guo X; Institute of Human Anatomy and Histology and Embryology, Otology & Neuroscience Center, Binzhou Medical University, Laishan District, Shandong Province, 264003,China.
Feng G; Institute of Human Anatomy and Histology and Embryology, Otology & Neuroscience Center, Binzhou Medical University, Laishan District, Shandong Province, 264003,China.
Ma Z; Institute of Human Anatomy and Histology and Embryology, Otology & Neuroscience Center, Binzhou Medical University, Laishan District, Shandong Province, 264003,China.
Huang W; Institute of Clinical Anatomy, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Huang F; Institute of Human Anatomy and Histology and Embryology, Otology & Neuroscience Center, Binzhou Medical University, Laishan District, Shandong Province, 264003,China.

Oncotarget ; 8(4): 6304-6318, 2017 Jan 24.

Article em En | MEDLINE | ID: mdl-27974673

Assuntos

Antineoplásicos/farmacologia; Neoplasias Encefálicas/tratamento farmacológico; Movimento Celular/efeitos dos fármacos; Proliferação de Células/efeitos dos fármacos; Resistencia a Medicamentos Antineoplásicos; Glioblastoma/tratamento farmacológico; MicroRNAs/metabolismo; Naftoquinonas/farmacologia; Animais; Subunidade Apc3 do Ciclossomo-Complexo Promotor de Anáfase/genética; Subunidade Apc3 do Ciclossomo-Complexo Promotor de Anáfase/metabolismo; Neoplasias Encefálicas/enzimologia; Neoplasias Encefálicas/genética; Neoplasias Encefálicas/patologia; Linhagem Celular Tumoral; Resistencia a Medicamentos Antineoplásicos/genética; Regulação Enzimológica da Expressão Gênica; Regulação Neoplásica da Expressão Gênica; Glioblastoma/enzimologia; Glioblastoma/genética; Glioblastoma/patologia; Humanos; Masculino; Camundongos Endogâmicos BALB C; Camundongos Nus; MicroRNAs/genética; Invasividade Neoplásica; Transdução de Sinais/efeitos dos fármacos; Fatores de Tempo; Transfecção; Carga Tumoral/efeitos dos fármacos; Ensaios Antitumorais Modelo de Xenoenxerto

Palavras-chave

CDC27; gliomas; invasion; mir-218-2; proliferation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Movimento Celular / Naftoquinonas / Glioblastoma / Resistencia a Medicamentos Antineoplásicos / MicroRNAs / Proliferação de Células / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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