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Design and Synthesis of Vandetanib Derivatives Containing Nitroimidazole Groups as Tyrosine Kinase Inhibitors in Normoxia and Hypoxia.
Wei, Huiqiang; Li, Deguan; Yang, Xiangbo; Shang, Haihua; Fan, Saijun; Li, Yiliang; Song, Dan.
Afiliação
  • Wei H; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College & Chinese Academy of Medical Sciences, Tianjin 300192, China. wakie0208@163.com.
  • Li D; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College & Chinese Academy of Medical Sciences, Tianjin 300192, China. ldguan@163.com.
  • Yang X; School of Petrochemical Engineering, Changzhou University, Changzhou 213164, China. 15122363480@163.com.
  • Shang H; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College & Chinese Academy of Medical Sciences, Tianjin 300192, China. shanghaihua2005@163.com.
  • Fan S; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College & Chinese Academy of Medical Sciences, Tianjin 300192, China. fansaijun@163.com.
  • Li Y; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College & Chinese Academy of Medical Sciences, Tianjin 300192, China. liyiliang@irm-cams.ac.cn.
  • Song D; Chongqing Technical Center for Drug Evaluation & Certification, Chongqing 400014, China. songdan1995@163.com.
Molecules ; 21(12)2016 Dec 14.
Article em En | MEDLINE | ID: mdl-27983649
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxigênio / Piperidinas / Quinazolinas / Proteínas Tirosina Quinases / Hipóxia Celular / Inibidores de Proteínas Quinases / Nitroimidazóis Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxigênio / Piperidinas / Quinazolinas / Proteínas Tirosina Quinases / Hipóxia Celular / Inibidores de Proteínas Quinases / Nitroimidazóis Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article