Anion Recognition as a Supramolecular Switch of Cell Internalization.
J Am Chem Soc
; 139(1): 55-58, 2017 01 11.
Article
em En
| MEDLINE
| ID: mdl-27984855
ABSTRACT
The cell internalization of designed oligoarginine peptides equipped with six glutamic acid residues and an anionic pyranine at the N-terminus is triggered upon addition of a supramolecular host. This host binds specifically to the pyranine moiety, enabling the complex to traverse the cell membrane. Interestingly, none of the components, neither the host nor the guest, are able to cross the cell membrane on their own.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Membrana Celular
/
Substâncias Macromoleculares
Limite:
Animals
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article