Construction of Chiral Tetraorganosilicons by Tandem Desymmetrization of Silacyclobutanes/Intermolecular Dehydrogenative Silylation.
Angew Chem Int Ed Engl
; 56(4): 1125-1129, 2017 01 19.
Article
em En
| MEDLINE
| ID: mdl-27990736
ABSTRACT
We report a method to construct chiral tetraorganosilicons by tandem silacyclobutane (SCB) desymmetrization-dehydrogenative silylations. A wide array of dibenzosiloles with stereogenic quaternary silicon centers were obtained in good yields and enantioselectivities up to 93 % ee. Chiral TMS-segphos was found to be a superior ligand in terms of reactivity and enantioselectivity.
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MEDLINE
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En
Ano de publicação:
2017
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Article