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RET Functions as a Dual-Specificity Kinase that Requires Allosteric Inputs from Juxtamembrane Elements.
Plaza-Menacho, Iván; Barnouin, Karin; Barry, Rachael; Borg, Annabel; Orme, Mariam; Chauhan, Rakhee; Mouilleron, Stephane; Martínez-Torres, Rubén J; Meier, Pascal; McDonald, Neil Q.
Afiliação
  • Plaza-Menacho I; Structural Biology Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK. Electronic address: ivan.plazamenacho@unibas.ch.
  • Barnouin K; Protein Analysis and Proteomics, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
  • Barry R; The Breast Cancer Now Toby Robins Research Centre, Mary-Jean Mitchell Green Building, Institute of Cancer Research, SW3 6JB London, UK.
  • Borg A; Protein Production Facility, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
  • Orme M; The Breast Cancer Now Toby Robins Research Centre, Mary-Jean Mitchell Green Building, Institute of Cancer Research, SW3 6JB London, UK.
  • Chauhan R; Structural Biology Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
  • Mouilleron S; Structural Biology Science Technology Platform, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
  • Martínez-Torres RJ; Structural Biology Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
  • Meier P; The Breast Cancer Now Toby Robins Research Centre, Mary-Jean Mitchell Green Building, Institute of Cancer Research, SW3 6JB London, UK.
  • McDonald NQ; Structural Biology Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK; Department of Biological Sciences, Institute of Structural and Molecular Biology, Birkbeck College, Malet Street, WC1E 7HX London, UK. Electronic address: neil.mcdonald@crick.ac.uk.
Cell Rep ; 17(12): 3319-3332, 2016 12 20.
Article em En | MEDLINE | ID: mdl-28009299
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Relação Estrutura-Atividade / Receptores Proteína Tirosina Quinases / Proteínas de Drosophila / Proteínas Proto-Oncogênicas c-ret Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Relação Estrutura-Atividade / Receptores Proteína Tirosina Quinases / Proteínas de Drosophila / Proteínas Proto-Oncogênicas c-ret Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article