Ebola virus VP35 blocks stress granule assembly.

Le Sage, Valerie; Cinti, Alessandro; McCarthy, Stephen; Amorim, Raquel; Rao, Shringar; Daino, Gian Luca; Tramontano, Enzo; Branch, Donald R; Mouland, Andrew J

Le Sage, Valerie; Cinti, Alessandro; McCarthy, Stephen; Amorim, Raquel; Rao, Shringar; Daino, Gian Luca; Tramontano, Enzo; Branch, Donald R; Mouland, Andrew J.

Afiliação

Le Sage V; HIV-1 RNA Trafficking Laboratory, Lady Davis Institute at the Jewish General Hospital, Montréal, Québec, Canada H3T 1E2.
Cinti A; HIV-1 RNA Trafficking Laboratory, Lady Davis Institute at the Jewish General Hospital, Montréal, Québec, Canada H3T 1E2; Department of Medicine, McGill University, Montréal, Québec, Canada H3A 0G4.
McCarthy S; Centre for Innovation, Canadian Blood Services, Toronto, Ontario, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Ontario, Toronto, Canada.
Amorim R; HIV-1 RNA Trafficking Laboratory, Lady Davis Institute at the Jewish General Hospital, Montréal, Québec, Canada H3T 1E2; Department of Medicine, McGill University, Montréal, Québec, Canada H3A 0G4.
Rao S; HIV-1 RNA Trafficking Laboratory, Lady Davis Institute at the Jewish General Hospital, Montréal, Québec, Canada H3T 1E2; Department of Microbiology and Immunology, McGill University, Montréal, Québec, Canada H3A 0G4.
Daino GL; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, SS 554, 09042 Monserrato, Cagliari, Italy.
Tramontano E; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, SS 554, 09042 Monserrato, Cagliari, Italy.
Branch DR; Centre for Innovation, Canadian Blood Services, Toronto, Ontario, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Ontario, Toronto, Canada.
Mouland AJ; HIV-1 RNA Trafficking Laboratory, Lady Davis Institute at the Jewish General Hospital, Montréal, Québec, Canada H3T 1E2; Department of Medicine, McGill University, Montréal, Québec, Canada H3A 0G4; Department of Microbiology and Immunology, McGill University, Montréal, Québec, Canada H3A 0G4. Electr

Virology ; 502: 73-83, 2017 02.

Article em En | MEDLINE | ID: mdl-28013103

Assuntos

Grânulos Citoplasmáticos/virologia; Ebolavirus/metabolismo; Doença pelo Vírus Ebola/virologia; Proteínas Virais Reguladoras e Acessórias/metabolismo; Proteínas de Transporte/metabolismo; Grânulos Citoplasmáticos/metabolismo; DNA Helicases; Ebolavirus/química; Ebolavirus/genética; Fator de Iniciação 2 em Eucariotos/metabolismo; Fator de Iniciação 3 em Eucariotos/metabolismo; Doença pelo Vírus Ebola/metabolismo; Interações Hospedeiro-Patógeno; Humanos; Proteínas de Ligação a Poli-ADP-Ribose; Ligação Proteica; Domínios Proteicos; RNA Helicases; Proteínas com Motivo de Reconhecimento de RNA; Proteínas Virais Reguladoras e Acessórias/química; Proteínas Virais Reguladoras e Acessórias/genética

Palavras-chave

Ebola virus; In vitro GST binding assay; Poliovirus infection; Proximity ligation assay; Stress granule assembly; TIAR recruitment; VP35; trVLP infection

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença pelo Vírus Ebola / Grânulos Citoplasmáticos / Ebolavirus / Proteínas Virais Reguladoras e Acessórias Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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