Histone H1 and Chromosomal Protein HMGN2 Regulate Prolactin-induced STAT5 Transcription Factor Recruitment and Function in Breast Cancer Cells.

Schauwecker, Suzanne M; Kim, J Julie; Licht, Jonathan D; Clevenger, Charles V

Schauwecker, Suzanne M; Kim, J Julie; Licht, Jonathan D; Clevenger, Charles V.

Afiliação

Schauwecker SM; From the Department of Pathology and.
Kim JJ; the Division of Reproductive Science in Medicine, Department of Obstetrics and Gynecology, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611.
Licht JD; the Division of Hematology and Oncology, Department of Medicine, University of Florida Health Cancer Center, Gainesville, Florida 32610, and.
Clevenger CV; the Department of Pathology, Virginia Commonwealth University, Richmond, Virginia 23298 charles.clevenger@vcuhealth.org.

J Biol Chem ; 292(6): 2237-2254, 2017 02 10.

Article em En | MEDLINE | ID: mdl-28035005

Assuntos

Neoplasias da Mama/metabolismo; Proteína HMGN2/fisiologia; Histonas/fisiologia; Prolactina/farmacologia; Fator de Transcrição STAT5/metabolismo; Neoplasias da Mama/patologia; Linhagem Celular Tumoral; Proliferação de Células; Feminino; Humanos; Processamento de Proteína Pós-Traducional; Fator de Transcrição STAT5/antagonistas & inibidores; Transcrição Gênica/fisiologia

Palavras-chave

STAT transcription factor; breast cancer; chromatin remodeling; linker histone H1; non-histone chromosomal protein HMG-17 (HMGN2); prolactin; prolactin receptor; signal transducers and activators of transcription 5 (STAT5); transcription regulation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Prolactina / Neoplasias da Mama / Histonas / Proteína HMGN2 / Fator de Transcrição STAT5 Limite: Female / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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