Epigenomics alternations and dynamic transcriptional changes in responses to 5-fluorouracil stimulation reveal mechanisms of acquired drug resistance of colorectal cancer cells.

Shen, Y; Tong, M; Liang, Q; Guo, Y; Sun, H Q; Zheng, W; Ao, L; Guo, Z; She, F

Shen, Y; Tong, M; Liang, Q; Guo, Y; Sun, H Q; Zheng, W; Ao, L; Guo, Z; She, F.

Afiliação

Shen Y; Department of Bioinformatics, Key Laboratory of Ministry of Education for Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China.
Tong M; Department of Bioinformatics, Key Laboratory of Ministry of Education for Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China.
Liang Q; Department of Bioinformatics, Key Laboratory of Ministry of Education for Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China.
Guo Y; Department of Preventive Medicine, School of Basic Medicine Sciences, Gannan Medical University, Ganzhou, China.
Sun HQ; Department of Bioinformatics, Key Laboratory of Ministry of Education for Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China.
Zheng W; Department of Bioinformatics, Key Laboratory of Ministry of Education for Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China.
Ao L; Department of Bioinformatics, Key Laboratory of Ministry of Education for Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China.
Guo Z; Department of Bioinformatics, Key Laboratory of Ministry of Education for Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China.
She F; Department of Bioinformatics, Key Laboratory of Ministry of Education for Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China.

Pharmacogenomics J ; 18(1): 23-28, 2018 01.

Article em En | MEDLINE | ID: mdl-28045128

Assuntos

Neoplasias Colorretais/tratamento farmacológico; Neoplasias Colorretais/genética; Resistencia a Medicamentos Antineoplásicos/efeitos dos fármacos; Resistencia a Medicamentos Antineoplásicos/genética; Fluoruracila/farmacologia; Transcrição Gênica/efeitos dos fármacos; Transcrição Gênica/genética; Linhagem Celular Tumoral; Metilação de DNA/efeitos dos fármacos; Metilação de DNA/genética; Epigênese Genética/efeitos dos fármacos; Epigênese Genética/genética; Epigenômica/métodos; Regulação Neoplásica da Expressão Gênica/efeitos dos fármacos; Regulação Neoplásica da Expressão Gênica/genética; Humanos

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transcrição Gênica / Neoplasias Colorretais / Resistencia a Medicamentos Antineoplásicos / Fluoruracila Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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