Pterostilbene attenuates high glucose-induced oxidative injury in hippocampal neuronal cells by activating nuclear factor erythroid 2-related factor 2.

Yang, Yang; Fan, Chongxi; Wang, Bodong; Ma, Zhiqiang; Wang, Dongjin; Gong, Bing; Di, Shouyin; Jiang, Shuai; Li, Yue; Li, Tian; Yang, Zhi; Luo, Erping

Yang, Yang; Fan, Chongxi; Wang, Bodong; Ma, Zhiqiang; Wang, Dongjin; Gong, Bing; Di, Shouyin; Jiang, Shuai; Li, Yue; Li, Tian; Yang, Zhi; Luo, Erping.

Afiliação

Yang Y; Department of Biomedical Engineering, The Fourth Military Medical University, 169 Changle West Road, Xi'an 710032, China; Department of Thoracic and Cardiovascular Surgery, Affiliated Drum Tower Hospital of Nanjing University Medical School, 321 Zhongshan Road, Nanjing 210008, Jiangsu, China. Electr
Fan C; Department of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, 1 Xinsi Road, Xi'an 710038, China.
Wang B; Graduate Management Team, The Fourth Military Medical University, 169 Changle West Road, Xi'an 710032, China.
Ma Z; Department of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, 1 Xinsi Road, Xi'an 710038, China.
Wang D; Department of Thoracic and Cardiovascular Surgery, Affiliated Drum Tower Hospital of Nanjing University Medical School, 321 Zhongshan Road, Nanjing 210008, Jiangsu, China.
Gong B; Department of Thoracic and Cardiovascular Surgery, Affiliated Drum Tower Hospital of Nanjing University Medical School, 321 Zhongshan Road, Nanjing 210008, Jiangsu, China.
Di S; Department of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, 1 Xinsi Road, Xi'an 710038, China.
Jiang S; Department of Aerospace Medicine, The Fourth Military Medical University, 169 Changle West Road, Xi'an 710032, China.
Li Y; Department of Biomedical Engineering, The Fourth Military Medical University, 169 Changle West Road, Xi'an 710032, China.
Li T; Department of Biomedical Engineering, The Fourth Military Medical University, 169 Changle West Road, Xi'an 710032, China.
Yang Z; Department of Biomedical Engineering, The Fourth Military Medical University, 169 Changle West Road, Xi'an 710032, China.
Luo E; Department of Biomedical Engineering, The Fourth Military Medical University, 169 Changle West Road, Xi'an 710032, China. Electronic address: erpingluo@126.com.

Biochim Biophys Acta Mol Basis Dis ; 1863(4): 827-837, 2017 04.

Article em En | MEDLINE | ID: mdl-28089584

Assuntos

Glucose/farmacologia; Hipocampo/metabolismo; Fator 2 Relacionado a NF-E2/metabolismo; Neurônios/metabolismo; Fármacos Neuroprotetores/farmacologia; Estresse Oxidativo/efeitos dos fármacos; Estilbenos/farmacologia; Linhagem Celular Tumoral; Citocromos c/genética; Citocromos c/metabolismo; Complexo I de Transporte de Elétrons/genética; Complexo I de Transporte de Elétrons/metabolismo; Complexo III da Cadeia de Transporte de Elétrons/genética; Complexo III da Cadeia de Transporte de Elétrons/metabolismo; Glucose/metabolismo; Hipocampo/patologia; Humanos; L-Lactato Desidrogenase/genética; L-Lactato Desidrogenase/metabolismo; Potencial da Membrana Mitocondrial/efeitos dos fármacos; Potencial da Membrana Mitocondrial/genética; Mitocôndrias/genética; Mitocôndrias/metabolismo; Mitocôndrias/patologia; Fator 2 Relacionado a NF-E2/genética; Neurônios/patologia; Oxirredução/efeitos dos fármacos; Estresse Oxidativo/genética; Espécies Reativas de Oxigênio/metabolismo

Palavras-chave

High glucose; Neuroprotection; Nuclear factor erythroid 2-related factor 2 signaling; Oxidative stress; Pterostilbene

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estilbenos / Estresse Oxidativo / Fármacos Neuroprotetores / Fator 2 Relacionado a NF-E2 / Glucose / Hipocampo / Neurônios Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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