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Proteomic Study of Blood Serum in Coronary Atherosclerosis.
Stakhneva, E M; Meshcheryakova, I A; Demidov, E A; Starostin, K V; Ragino, Yu I; Peltek, S E; Voevoda, M I.
Afiliação
  • Stakhneva EM; Research Institute of Internal and Preventive Medicine, Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia. stakhneva@yandex.ru.
  • Meshcheryakova IA; Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia.
  • Demidov EA; Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia.
  • Starostin KV; Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia.
  • Ragino YI; Research Institute of Internal and Preventive Medicine, Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia.
  • Peltek SE; Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia.
  • Voevoda MI; Research Institute of Internal and Preventive Medicine, Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia.
Bull Exp Biol Med ; 162(3): 343-345, 2017 Jan.
Article em En | MEDLINE | ID: mdl-28091899
Changes in the blood serum proteins were assessed in men with coronary atherosclerosis and without coronary heart disease. Proteins were separated by 2D-electrophoresis, protein fractions were identified by their peptide fingerprint by MALDI method; fractions with more than twofold increase in protein level were determined. In blood serum of patients with coronary atherosclerosis, the content of C4 complement protein increased and ceruloplasmin level decreased, which is typical of heart failure and coronary heart disease.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença da Artéria Coronariana / Ceruloplasmina / Complemento C4 Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies Limite: Adult / Humans / Male / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença da Artéria Coronariana / Ceruloplasmina / Complemento C4 Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies Limite: Adult / Humans / Male / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article