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Evaluating the therapeutic potential of idebenone and related quinone analogues in Leber hereditary optic neuropathy.
Yu-Wai-Man, Patrick; Soiferman, Devorah; Moore, David G; Burté, Florence; Saada, Ann.
Afiliação
  • Yu-Wai-Man P; Wellcome Trust Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK; Newcastle Eye Centre, Royal Victoria Infirmary, Newcastle upon Tyne, UK; NIHR Biomedical Research Centre at Moorfields Eye Hospital and UCL Institute of Ophthalmology, Lond
  • Soiferman D; Monique and Jacques Roboh Department of Genetic Research, Hadassah-Hebrew University Medical Center, Jerusalem, Israel; Department of Genetics and Metabolic Diseases, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
  • Moore DG; Wellcome Trust Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK.
  • Burté F; Wellcome Trust Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK.
  • Saada A; Monique and Jacques Roboh Department of Genetic Research, Hadassah-Hebrew University Medical Center, Jerusalem, Israel; Department of Genetics and Metabolic Diseases, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Mitochondrion ; 36: 36-42, 2017 09.
Article em En | MEDLINE | ID: mdl-28093355

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quinonas / Trifosfato de Adenosina / Ubiquinona / Espécies Reativas de Oxigênio / Atrofia Óptica Hereditária de Leber / Fibroblastos / Antioxidantes Limite: Adolescent / Adult / Humans / Male / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quinonas / Trifosfato de Adenosina / Ubiquinona / Espécies Reativas de Oxigênio / Atrofia Óptica Hereditária de Leber / Fibroblastos / Antioxidantes Limite: Adolescent / Adult / Humans / Male / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article