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Immature Core protein of hepatitis C virus induces an unfolded protein response through inhibition of ERAD-L in a yeast model system.
Takahashi, Shota; Sato, Naoko; Kikuchi, Junichi; Kakinuma, Hideaki; Okawa, Jun; Masuyama, Yukiko; Iwasa, Singo; Irokawa, Hayato; Hwang, Gi-Wook; Naganuma, Akira; Kohara, Michinori; Kuge, Shusuke.
Afiliação
  • Takahashi S; Department of Microbiology, Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai, Miyagi, 981-8558, Japan.
  • Sato N; Department of Microbiology, Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai, Miyagi, 981-8558, Japan.
  • Kikuchi J; Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba-ku, Sendai, Miyagi, 980-8578, Japan.
  • Kakinuma H; Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba-ku, Sendai, Miyagi, 980-8578, Japan.
  • Okawa J; Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba-ku, Sendai, Miyagi, 980-8578, Japan.
  • Masuyama Y; Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba-ku, Sendai, Miyagi, 980-8578, Japan.
  • Iwasa S; Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba-ku, Sendai, Miyagi, 980-8578, Japan.
  • Irokawa H; Department of Microbiology, Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai, Miyagi, 981-8558, Japan.
  • Hwang GW; Department of Microbiology, Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai, Miyagi, 981-8558, Japan.
  • Naganuma A; Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba-ku, Sendai, Miyagi, 980-8578, Japan.
  • Kohara M; Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba-ku, Sendai, Miyagi, 980-8578, Japan.
  • Kuge S; Department of Microbiology and Cell Biology, Tokyo Metropolitan Institute of Medical Science, Kamikitazawa, Setagaya-ku, Tokyo, 156-8506, Japan.
Genes Cells ; 22(2): 160-173, 2017 Feb.
Article em En | MEDLINE | ID: mdl-28097745
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Saccharomyces cerevisiae / Proteínas do Core Viral / Hepacivirus / Resposta a Proteínas não Dobradas / Degradação Associada com o Retículo Endoplasmático Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Saccharomyces cerevisiae / Proteínas do Core Viral / Hepacivirus / Resposta a Proteínas não Dobradas / Degradação Associada com o Retículo Endoplasmático Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article