Crystallization and preliminary X-ray investigation of a complex between a Fab fragment and its antigen, cyclosporin.
J Mol Biol
; 209(1): 177-8, 1989 Sep 05.
Article
em En
| MEDLINE
| ID: mdl-2810368
ABSTRACT
Preliminary crystallographic data are given for a complex between the cyclic undecapeptide cyclosporin and the Fab fragment of an anti-cyclosporin monoclonal antibody. Crystals of the complex are orthorhombic with space group P2(1)2(1)2(1) and diffract to 2.7 A resolution. The unit cell dimensions are a = 52.6 A, b = 70.2 A and c = 118.4 A. A native data set to 2.7 A resolution has been collected.
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Base de dados:
MEDLINE
Assunto principal:
Fragmentos Fab das Imunoglobulinas
/
Ciclosporinas
Idioma:
En
Ano de publicação:
1989
Tipo de documento:
Article