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An ultra-sensitive LC-MS/MS method to determine midazolam levels in human plasma: development, validation and application to a clinical study.
Chen, Mu; Lu, Wenzhe; Lu, Yang; Kang, Lijuan; Zhao, Harry; Lin, Zhongping John; Wang, Weimin; Fraier, Daniela; Ottaviani, Giorgio.
Afiliação
  • Chen M; Frontage Laboratories Inc., 700 Pennsylvania Drive, Exton, PA 19341, USA.
  • Lu W; Roche Innovation Center Shanghai, 720 Cai Lun Road, Building 5/917 Ha Lei Road, Building 6, Pudong, Shanghai 201203, China.
  • Lu Y; Frontage Laboratories Inc., 700 Pennsylvania Drive, Exton, PA 19341, USA.
  • Kang L; Frontage Laboratories Inc., 700 Pennsylvania Drive, Exton, PA 19341, USA.
  • Zhao H; Frontage Laboratories Inc., 700 Pennsylvania Drive, Exton, PA 19341, USA.
  • Lin ZJ; Frontage Laboratories Inc., 700 Pennsylvania Drive, Exton, PA 19341, USA.
  • Wang W; Frontage Laboratories Inc., 700 Pennsylvania Drive, Exton, PA 19341, USA.
  • Fraier D; Roche Innovation Center Switzerland, F. Hoffmann-La Roche Ltd, Grenzacherstrasse 124, CH-4070 Basel, Switzerland.
  • Ottaviani G; Roche Innovation Center Shanghai, 720 Cai Lun Road, Building 5/917 Ha Lei Road, Building 6, Pudong, Shanghai 201203, China.
Bioanalysis ; 9(3): 297-312, 2017 Feb.
Article em En | MEDLINE | ID: mdl-28111961
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Midazolam / Cromatografia Líquida / Espectrometria de Massas em Tandem Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Midazolam / Cromatografia Líquida / Espectrometria de Massas em Tandem Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article