The JAK2V617F mutation in normal individuals takes place in differentiating cells.

Krichevsky, Svetlana; Prus, Eugenia; Perlman, Riki; Fibach, Eitan; Ben-Yehuda, Dina

Krichevsky, Svetlana; Prus, Eugenia; Perlman, Riki; Fibach, Eitan; Ben-Yehuda, Dina.

Afiliação

Krichevsky S; Division of Hematology, Hadassah - Hebrew University Medical Center, Jerusalem, Israel.
Prus E; Division of Hematology, Hadassah - Hebrew University Medical Center, Jerusalem, Israel.
Perlman R; Division of Hematology, Hadassah - Hebrew University Medical Center, Jerusalem, Israel.
Fibach E; Division of Hematology, Hadassah - Hebrew University Medical Center, Jerusalem, Israel. Electronic address: Fibach@yahoo.com.
Ben-Yehuda D; Division of Hematology, Hadassah - Hebrew University Medical Center, Jerusalem, Israel.

Blood Cells Mol Dis ; 63: 45-51, 2017 03.

Article em En | MEDLINE | ID: mdl-28126623

Assuntos

Diferenciação Celular/genética; Janus Quinase 2/genética; Taxa de Mutação; Animais; Doadores de Sangue; Células Precursoras Eritroides/citologia; Eritropoetina/farmacologia; Humanos; Camundongos; Mutação; Transtornos Mieloproliferativos

Palavras-chave

DNA repair; Erythroid differentiation; Myeloproliferative neoplasms; The JAK2V617F mutation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diferenciação Celular / Janus Quinase 2 / Taxa de Mutação Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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