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Correcting miR92a-vGAT-Mediated GABAergic Dysfunctions Rescues Human Tau-Induced Anxiety in Mice.
Li, Xiaoguang; Wang, Zhihao; Tan, Lu; Wang, Yali; Lu, Chengbiao; Chen, Rongxiang; Zhang, Shujuan; Gao, Yuan; Liu, Yanchao; Yin, Yaling; Liu, Xinghua; Liu, Enjie; Yang, Ying; Hu, Yu; Xu, Zhipeng; Xu, Fuqiang; Wang, Jie; Liu, Gong-Ping; Wang, Jian-Zhi.
Afiliação
  • Li X; Department of Pathophysiology, School of Basic Medicine and Collaborative Innovation Center for Brain Science, Key Laboratory of Ministry of Education of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
  • Wang Z; Department of Pathophysiology, School of Basic Medicine and Collaborative Innovation Center for Brain Science, Key Laboratory of Ministry of Education of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
  • Tan L; Key Laboratory for Molecular Diagnosis of Hubei Province, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430014, China.
  • Wang Y; Department of Pathophysiology, School of Basic Medicine and Collaborative Innovation Center for Brain Science, Key Laboratory of Ministry of Education of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; Physiology Departmen
  • Lu C; Physiology Department, Henan Provincial Key Laboratory for Brain Research, Xinxiang Medical University, Xinxiang 453000, China.
  • Chen R; State Key Laboratory for Magnet Resonance and Atom and Molecular Physics, Wuhan Institute of Physics and Mathematics, Chinese Academia of Science, Wuhan 430071, China.
  • Zhang S; Department of Pathophysiology, School of Basic Medicine and Collaborative Innovation Center for Brain Science, Key Laboratory of Ministry of Education of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
  • Gao Y; Department of Pathophysiology, School of Basic Medicine and Collaborative Innovation Center for Brain Science, Key Laboratory of Ministry of Education of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
  • Liu Y; Department of Pathophysiology, School of Basic Medicine and Collaborative Innovation Center for Brain Science, Key Laboratory of Ministry of Education of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
  • Yin Y; Department of Pathophysiology, School of Basic Medicine and Collaborative Innovation Center for Brain Science, Key Laboratory of Ministry of Education of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
  • Liu X; Department of Pathophysiology, School of Basic Medicine and Collaborative Innovation Center for Brain Science, Key Laboratory of Ministry of Education of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
  • Liu E; Department of Pathophysiology, School of Basic Medicine and Collaborative Innovation Center for Brain Science, Key Laboratory of Ministry of Education of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
  • Yang Y; Department of Pathophysiology, School of Basic Medicine and Collaborative Innovation Center for Brain Science, Key Laboratory of Ministry of Education of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
  • Hu Y; Department of Pathophysiology, School of Basic Medicine and Collaborative Innovation Center for Brain Science, Key Laboratory of Ministry of Education of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
  • Xu Z; Department of Pathophysiology, School of Basic Medicine and Collaborative Innovation Center for Brain Science, Key Laboratory of Ministry of Education of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
  • Xu F; State Key Laboratory for Magnet Resonance and Atom and Molecular Physics, Wuhan Institute of Physics and Mathematics, Chinese Academia of Science, Wuhan 430071, China.
  • Wang J; State Key Laboratory for Magnet Resonance and Atom and Molecular Physics, Wuhan Institute of Physics and Mathematics, Chinese Academia of Science, Wuhan 430071, China.
  • Liu GP; Department of Pathophysiology, School of Basic Medicine and Collaborative Innovation Center for Brain Science, Key Laboratory of Ministry of Education of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; Co-innovation Center
  • Wang JZ; Department of Pathophysiology, School of Basic Medicine and Collaborative Innovation Center for Brain Science, Key Laboratory of Ministry of Education of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; Co-innovation Center
Mol Ther ; 25(1): 140-152, 2017 01 04.
Article em En | MEDLINE | ID: mdl-28129110
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ansiedade / Tauopatias / MicroRNAs / Proteínas da Membrana Plasmática de Transporte de GABA / Neurônios GABAérgicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ansiedade / Tauopatias / MicroRNAs / Proteínas da Membrana Plasmática de Transporte de GABA / Neurônios GABAérgicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article