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Pirfenidone exerts antifibrotic effects through inhibition of GLI transcription factors.
Didiasova, Miroslava; Singh, Rajeev; Wilhelm, Jochen; Kwapiszewska, Grazyna; Wujak, Lukasz; Zakrzewicz, Dariusz; Schaefer, Liliana; Markart, Philipp; Seeger, Werner; Lauth, Matthias; Wygrecka, Malgorzata.
Afiliação
  • Didiasova M; Department of Biochemistry, Universities of Giessen and Marburg Lung Center, Giessen, Germany.
  • Singh R; Institute of Molecular Biology and Tumor Research (IMT), Center for Tumor Biology and Immunology, Philipps University, Marburg, Germany.
  • Wilhelm J; Department of Internal Medicine, Universities of Giessen and Marburg Lung Center, Giessen, Germany.
  • Kwapiszewska G; German Center for Lung Research, Justus-Liebig University, Giessen, Germany.
  • Wujak L; Ludwig Boltzmann Institute for Lung Vascular Research, Graz, Austria; and.
  • Zakrzewicz D; Department of Biochemistry, Universities of Giessen and Marburg Lung Center, Giessen, Germany.
  • Schaefer L; Department of Biochemistry, Universities of Giessen and Marburg Lung Center, Giessen, Germany.
  • Markart P; Institute of Pharmacology and Toxicology, Goethe University School of Medicine, Frankfurt am Main, Germany.
  • Seeger W; Department of Internal Medicine, Universities of Giessen and Marburg Lung Center, Giessen, Germany.
  • Lauth M; German Center for Lung Research, Justus-Liebig University, Giessen, Germany.
  • Wygrecka M; Department of Internal Medicine, Universities of Giessen and Marburg Lung Center, Giessen, Germany.
FASEB J ; 31(5): 1916-1928, 2017 05.
Article em En | MEDLINE | ID: mdl-28148565
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piridonas / Proteínas Nucleares / Proliferação de Células / Fatores de Transcrição Kruppel-Like / Fibrose Pulmonar Idiopática / Fibroblastos Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piridonas / Proteínas Nucleares / Proliferação de Células / Fatores de Transcrição Kruppel-Like / Fibrose Pulmonar Idiopática / Fibroblastos Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article