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Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination.
Pardi, Norbert; Hogan, Michael J; Pelc, Rebecca S; Muramatsu, Hiromi; Andersen, Hanne; DeMaso, Christina R; Dowd, Kimberly A; Sutherland, Laura L; Scearce, Richard M; Parks, Robert; Wagner, Wendeline; Granados, Alex; Greenhouse, Jack; Walker, Michelle; Willis, Elinor; Yu, Jae-Sung; McGee, Charles E; Sempowski, Gregory D; Mui, Barbara L; Tam, Ying K; Huang, Yan-Jang; Vanlandingham, Dana; Holmes, Veronica M; Balachandran, Harikrishnan; Sahu, Sujata; Lifton, Michelle; Higgs, Stephen; Hensley, Scott E; Madden, Thomas D; Hope, Michael J; Karikó, Katalin; Santra, Sampa; Graham, Barney S; Lewis, Mark G; Pierson, Theodore C; Haynes, Barton F; Weissman, Drew.
Afiliação
  • Pardi N; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
  • Hogan MJ; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
  • Pelc RS; Viral Pathogenesis Section, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland 20892, USA.
  • Muramatsu H; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
  • Andersen H; Bioqual Inc., Rockville, Maryland 20850-3220, USA.
  • DeMaso CR; Viral Pathogenesis Section, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland 20892, USA.
  • Dowd KA; Viral Pathogenesis Section, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland 20892, USA.
  • Sutherland LL; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina 27710, USA.
  • Scearce RM; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina 27710, USA.
  • Parks R; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina 27710, USA.
  • Wagner W; Bioqual Inc., Rockville, Maryland 20850-3220, USA.
  • Granados A; Bioqual Inc., Rockville, Maryland 20850-3220, USA.
  • Greenhouse J; Bioqual Inc., Rockville, Maryland 20850-3220, USA.
  • Walker M; Bioqual Inc., Rockville, Maryland 20850-3220, USA.
  • Willis E; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
  • Yu JS; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina 27710, USA.
  • McGee CE; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina 27710, USA.
  • Sempowski GD; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina 27710, USA.
  • Mui BL; Acuitas Therapeutics, Vancouver, British Columbia V6T 1Z3, Canada.
  • Tam YK; Acuitas Therapeutics, Vancouver, British Columbia V6T 1Z3, Canada.
  • Huang YJ; Diagnostic Medicine and Pathobiology, College of Veterinary Medicine and the Biosecurity Research Institute, Kansas State University, Manhattan, Kansas 66506, USA.
  • Vanlandingham D; Diagnostic Medicine and Pathobiology, College of Veterinary Medicine and the Biosecurity Research Institute, Kansas State University, Manhattan, Kansas 66506, USA.
  • Holmes VM; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
  • Balachandran H; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215 USA.
  • Sahu S; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215 USA.
  • Lifton M; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215 USA.
  • Higgs S; Diagnostic Medicine and Pathobiology, College of Veterinary Medicine and the Biosecurity Research Institute, Kansas State University, Manhattan, Kansas 66506, USA.
  • Hensley SE; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
  • Madden TD; Acuitas Therapeutics, Vancouver, British Columbia V6T 1Z3, Canada.
  • Hope MJ; Acuitas Therapeutics, Vancouver, British Columbia V6T 1Z3, Canada.
  • Karikó K; BioNTech RNA Pharmaceuticals, An der Goldgrube 12, 55131 Mainz, Germany.
  • Santra S; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215 USA.
  • Graham BS; Vaccine Research Center, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland 20892, USA.
  • Lewis MG; Bioqual Inc., Rockville, Maryland 20850-3220, USA.
  • Pierson TC; Viral Pathogenesis Section, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland 20892, USA.
  • Haynes BF; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina 27710, USA.
  • Weissman D; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Nature ; 543(7644): 248-251, 2017 03 09.
Article em En | MEDLINE | ID: mdl-28151488
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: RNA Mensageiro / Vacinas Virais / Zika virus / Infecção por Zika virus Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: RNA Mensageiro / Vacinas Virais / Zika virus / Infecção por Zika virus Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article