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A phase 1/2a, dose-escalation, safety, pharmacokinetic, and preliminary efficacy study of intraperitoneal administration of BC-819 (H19-DTA) in subjects with recurrent ovarian/peritoneal cancer.
Lavie, Ofer; Edelman, David; Levy, Tally; Fishman, Ami; Hubert, Ayala; Segev, Yakir; Raveh, Eli; Gilon, Michal; Hochberg, Avraham.
Afiliação
  • Lavie O; Department of Obstetrics and Gynecology Carmel Medical Center, The Rappaport Faculty of Medicine, Technion, Haifa, Israel.
  • Edelman D; Sharett Institute of Oncology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
  • Levy T; Department of Obstetrics and Gynecology, The Edith Wolfson Medical Center-Holon, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
  • Fishman A; Department of Gynecology and Obstetrics, Meir Hospital Kfar-Saba, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
  • Hubert A; Sharett Institute of Oncology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
  • Segev Y; Department of Obstetrics and Gynecology Carmel Medical Center, The Rappaport Faculty of Medicine, Technion, Haifa, Israel.
  • Raveh E; BioCancell Therapeutics Ltd, Jerusalem, Israel. Eli.Raveh@mail.huji.ac.il.
  • Gilon M; The Department of Biological Chemistry, Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel. Eli.Raveh@mail.huji.ac.il.
  • Hochberg A; BioCancell Therapeutics Ltd, Jerusalem, Israel.
Arch Gynecol Obstet ; 295(3): 751-761, 2017 Mar.
Article em En | MEDLINE | ID: mdl-28154921
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Neoplasias Peritoneais / Plasmídeos / Terapia Genética / Toxina Diftérica / RNA Longo não Codificante / Recidiva Local de Neoplasia Tipo de estudo: Clinical_trials Limite: Adult / Aged / Female / Humans / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Neoplasias Peritoneais / Plasmídeos / Terapia Genética / Toxina Diftérica / RNA Longo não Codificante / Recidiva Local de Neoplasia Tipo de estudo: Clinical_trials Limite: Adult / Aged / Female / Humans / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article