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The host cell response to tick-borne encephalitis virus.
Carletti, Tea; Zakaria, Mohammad Khalid; Marcello, Alessandro.
Afiliação
  • Carletti T; Laboratory of Molecular Virology, International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy.
  • Zakaria MK; Laboratory of Molecular Virology, International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy.
  • Marcello A; Laboratory of Molecular Virology, International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy. Electronic address: marcello@icgeb.org.
Biochem Biophys Res Commun ; 492(4): 533-540, 2017 10 28.
Article em En | MEDLINE | ID: mdl-28167278
Tick-borne encephalitis virus is the most prevalent autochthonous arbovirus in Europe and an important travel-associated virus. Complications of the infection could lead to lethal encephalitis in susceptible individuals. However, despite its clinical relevance and expanding geographical distribution, most of our knowledge on its pathogenesis is inferred from studies on other flaviviruses. Molecular details of the host cell response to infection are scarce leading to a poor understanding of the antiviral pathways and viral countermeasures that are critical to determine the outcome of the infection. In this work the relevant literature is reviewed and the key elements of tick-borne encephalitis virus infection of human cells are identified, which requires further investigation.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Encéfalo / Infecções por Flavivirus / Encefalite Transmitida por Carrapatos / Vírus da Encefalite Transmitidos por Carrapatos Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Encéfalo / Infecções por Flavivirus / Encefalite Transmitida por Carrapatos / Vírus da Encefalite Transmitidos por Carrapatos Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article