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Cell population structure prior to bifurcation predicts efficiency of directed differentiation in human induced pluripotent cells.
Bargaje, Rhishikesh; Trachana, Kalliopi; Shelton, Martin N; McGinnis, Christopher S; Zhou, Joseph X; Chadick, Cora; Cook, Savannah; Cavanaugh, Christopher; Huang, Sui; Hood, Leroy.
Afiliação
  • Bargaje R; Institute for Systems Biology, Seattle, WA 98109.
  • Trachana K; Institute for Systems Biology, Seattle, WA 98109.
  • Shelton MN; Institute for Systems Biology, Seattle, WA 98109.
  • McGinnis CS; Institute for Systems Biology, Seattle, WA 98109.
  • Zhou JX; Institute for Systems Biology, Seattle, WA 98109.
  • Chadick C; Institute for Systems Biology, Seattle, WA 98109.
  • Cook S; Institute for Stem Cell & Regenerative Medicine, University of Washington Medicine Research, Seattle, WA 98109.
  • Cavanaugh C; Institute for Stem Cell & Regenerative Medicine, University of Washington Medicine Research, Seattle, WA 98109.
  • Huang S; Institute for Systems Biology, Seattle, WA 98109; sui.huang@systemsbiology.org Leroy.Hood@systemsbiology.org.
  • Hood L; Institute for Systems Biology, Seattle, WA 98109; sui.huang@systemsbiology.org Leroy.Hood@systemsbiology.org.
Proc Natl Acad Sci U S A ; 114(9): 2271-2276, 2017 02 28.
Article em En | MEDLINE | ID: mdl-28167799
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Diferenciação Celular / Regulação da Expressão Gênica no Desenvolvimento / Miócitos Cardíacos / Células-Tronco Pluripotentes Induzidas / Transcriptoma Tipo de estudo: Prognostic_studies / Qualitative_research / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Diferenciação Celular / Regulação da Expressão Gênica no Desenvolvimento / Miócitos Cardíacos / Células-Tronco Pluripotentes Induzidas / Transcriptoma Tipo de estudo: Prognostic_studies / Qualitative_research / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article