Englerins: A Comprehensive Review.
J Nat Prod
; 80(3): 771-781, 2017 03 24.
Article
em En
| MEDLINE
| ID: mdl-28170253
ABSTRACT
In the decade since the discovery of englerin A (1) and its potent activity in cancer models, this natural product and its analogues have been the subject of numerous chemical, biological, and preclinical studies by many research groups. This review summarizes published findings and proposes further research directions required for entry of an englerin analogue into clinical trials for kidney cancer and other conditions.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Sesquiterpenos de Guaiano
/
Neoplasias Renais
/
Antineoplásicos Fitogênicos
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article