Identification by next-generation sequencing of Aichivirus B in a calf with enterocolitis and neurologic signs.
J Vet Diagn Invest
; 29(2): 208-211, 2017 Mar.
Article
em En
| MEDLINE
| ID: mdl-28176615
ABSTRACT
An 11-d-old Holstein bull calf was presented to the Veterinary Medical Teaching Hospital at the University of Wisconsin-Madison because of a 4-d history of diarrhea and persistent low-grade fever. Initial diagnosis was enteritis caused by Cryptosporidium and rotavirus. During hospitalization, the calf became stuporous and was only responsive to noxious stimuli, with hypotonia of all 4 limbs, tail, head, and neck. A cerebrospinal fluid analysis revealed xanthochromia, with marked lymphocytic pleocytosis, which was suggestive of viral meningitis and/or encephalitis. Aichivirus B, which belongs to the Kobuvirus genus, was tentatively identified in spinal fluid by next-generation DNA sequencing. This virus can affect a multitude of species, including humans and cattle, and has been isolated from both healthy and diarrheic individuals. However, to date, a possible connection with neurologic disease has not been described, to our knowledge.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Doenças dos Bovinos
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Infecções por Picornaviridae
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Kobuvirus
Tipo de estudo:
Diagnostic_studies
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Prognostic_studies
Limite:
Animals
País como assunto:
America do norte
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article