Dimethyl Itaconate Is Not Metabolized into Itaconate Intracellularly.

ElAzzouny, Mahmoud; Tom, Christopher T M B; Evans, Charles R; Olson, Lori L; Tanga, Mary J; Gallagher, Katherine A; Martin, Brent R; Burant, Charles F

ElAzzouny, Mahmoud; Tom, Christopher T M B; Evans, Charles R; Olson, Lori L; Tanga, Mary J; Gallagher, Katherine A; Martin, Brent R; Burant, Charles F.

Afiliação

ElAzzouny M; From the Departments of Internal Medicine.
Tom CT; Chemistry, and.
Evans CR; From the Departments of Internal Medicine.
Olson LL; SRI International, Menlo Park, California 94025.
Tanga MJ; SRI International, Menlo Park, California 94025.
Gallagher KA; Surgery, University of Michigan, Ann Arbor, Michigan 48105 and.
Martin BR; Chemistry, and.
Burant CF; From the Departments of Internal Medicine.

J Biol Chem ; 292(12): 4766-4769, 2017 03 24.

Article em En | MEDLINE | ID: mdl-28188288

Assuntos

Inflamação/metabolismo; Macrófagos/metabolismo; Metaboloma; Succinatos/metabolismo; Animais; Células Cultivadas; Lipopolissacarídeos/metabolismo; Metabolômica; Camundongos; Camundongos Endogâmicos C57BL; Células RAW 264.7; Ácido Succínico/metabolismo

Palavras-chave

dimethyl-itaconate; inflammation; isotopic tracer; itaconic acid; macrophage; mass spectrometry (MS); metabolomics

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Succinatos / Metaboloma / Inflamação / Macrófagos Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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