Nrf2 mediates redox adaptation in NOX4-overexpressed non-small cell lung cancer cells.

Wu, Qipeng; Yao, Bei; Li, Ning; Ma, Lei; Deng, Yanchao; Yang, Yang; Zeng, Cheng; Yang, Zhicheng; Liu, Bing

Wu, Qipeng; Yao, Bei; Li, Ning; Ma, Lei; Deng, Yanchao; Yang, Yang; Zeng, Cheng; Yang, Zhicheng; Liu, Bing.

Afiliação

Wu Q; Department of Clinical Pharmacy, School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Yao B; Department of Clinical Pharmacy, School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Li N; Department of Clinical Pharmacy, School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Ma L; Department of Clinical Pharmacy, School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Deng Y; Department of Clinical Pharmacy, School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Yang Y; Department of Clinical Pharmacy, School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Zeng C; Department of Clinical Pharmacy, School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Yang Z; Department of Clinical Pharmacy, School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Liu B; Department of Clinical Pharmacy, School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China; Guangdong Key Laboratory of Pharmaceutical Bioactive Substances, Guangdong Pharmaceutical University, Guangzhou 510006, China. Electronic address: liubing520@gdpu.edu.cn.

Exp Cell Res ; 352(2): 245-254, 2017 03 15.

Article em En | MEDLINE | ID: mdl-28196727

Assuntos

Carcinoma Pulmonar de Células não Pequenas/metabolismo; Neoplasias Pulmonares/metabolismo; NADPH Oxidases/metabolismo; Fator 2 Relacionado a NF-E2/metabolismo; Estresse Oxidativo; Adaptação Fisiológica; Apoptose; Linhagem Celular Tumoral; Glutationa/metabolismo; Humanos; Peróxido de Hidrogênio/metabolismo; NADPH Oxidase 4; NADPH Oxidases/genética; Fator 2 Relacionado a NF-E2/genética; Oxirredução; Fosfatidilinositol 3-Quinases/metabolismo; Proteólise; Transdução de Sinais

Palavras-chave

Apoptosis resistance; NOX4; NSCLC; Nrf2; Redox adaptation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Estresse Oxidativo / NADPH Oxidases / Fator 2 Relacionado a NF-E2 / Neoplasias Pulmonares Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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