Mannan-binding lectin, a serum collectin, suppresses T-cell proliferation <i>via</i> direct interaction with cell surface calreticulin and inhibition of proximal T-cell receptor signaling.

Zhao, Na; Wu, Jie; Xiong, Simin; Zhang, Liyun; Lu, Xiao; Chen, Shangliang; Wu, Qifeng; Wang, Hailan; Liu, Ying; Chen, Zhengliang; Zuo, Daming

Mannan-binding lectin, a serum collectin, suppresses T-cell proliferation via direct interaction with cell surface calreticulin and inhibition of proximal T-cell receptor signaling.

Zhao, Na; Wu, Jie; Xiong, Simin; Zhang, Liyun; Lu, Xiao; Chen, Shangliang; Wu, Qifeng; Wang, Hailan; Liu, Ying; Chen, Zhengliang; Zuo, Daming.

Afiliação

Zhao N; Department of Immunology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Wu J; Department of Occupational Medicine, Guangdong Province Hospital for Occupational Disease Prevention and Treatment, Guangzhou, China.
Xiong S; Department of Occupational Medicine, Guangdong Province Hospital for Occupational Disease Prevention and Treatment, Guangzhou, China.
Zhang L; School of Public Health, Shanxi Medical University, Taiyuan, China; and.
Lu X; Department of Immunology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Chen S; Department of Immunology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Wu Q; Department of Immunology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Wang H; Department of Immunology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Liu Y; Department of Occupational Medicine, Guangdong Province Hospital for Occupational Disease Prevention and Treatment, Guangzhou, China.
Chen Z; Department of Occupational Medicine, Guangdong Province Hospital for Occupational Disease Prevention and Treatment, Guangzhou, China.
Zuo D; School of Public Health, Shanxi Medical University, Taiyuan, China; and.

FASEB J ; 31(6): 2405-2417, 2017 06.

Article em En | MEDLINE | ID: mdl-28209773

Assuntos

Calreticulina/metabolismo; Proliferação de Células/fisiologia; Leucócitos Mononucleares/metabolismo; Lectina de Ligação a Manose/metabolismo; Linfócitos T/fisiologia; Calreticulina/genética; Pontos de Checagem do Ciclo Celular; Regulação da Expressão Gênica/fisiologia; Humanos; Receptores de Antígenos de Linfócitos T; Transdução de Sinais; Silicose

Palavras-chave

T-cell activation; cell cycle; silicosis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucócitos Mononucleares / Linfócitos T / Calreticulina / Lectina de Ligação a Manose / Proliferação de Células Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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