Early and continued manual stimulation is required for long-term recovery after facial nerve injury.
Muscle Nerve
; 57(1): 100-106, 2018 Jan.
Article
em En
| MEDLINE
| ID: mdl-28214333
ABSTRACT
INTRODUCTION:
We previously have shown that manual stimulation (MS) of vibrissal muscles for 2 months after facial nerve injury in rats improves whisking and reduces motor end plate polyinnervation. Here, we seek to determine whether discontinuing or delaying MS after facial-facial anastomosis (FFA) leads to similar results.METHODS:
Rats were subjected to FFA and received MS for (1) 4 months (early and continued), (2) the first but not the last 2 months (discontinued), or (3) the last 2 months (delayed). Intact animals and those not receiving MS (no MS) were also examined.RESULTS:
Early and continued MS restored whisking amplitude to 43°, a value significantly higher compared with the discontinued, delayed, and no MS groups (32°, 24°, and 10°, respectively). Motor end plate polyinnervation occurred in all experimental groups but was significantly higher in the delayed group.DISCUSSION:
Early and continued MS results in better recovery than when it is either discontinued or delayed. Muscle Nerve 57 100-106, 2018.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Estimulação Física
/
Traumatismos do Nervo Facial
Limite:
Animals
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article