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Complement drives glucosylceramide accumulation and tissue inflammation in Gaucher disease.
Pandey, Manoj K; Burrow, Thomas A; Rani, Reena; Martin, Lisa J; Witte, David; Setchell, Kenneth D; Mckay, Mary A; Magnusen, Albert F; Zhang, Wujuan; Liou, Benjamin; Köhl, Jörg; Grabowski, Gregory A.
Afiliação
  • Pandey MK; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.
  • Burrow TA; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.
  • Rani R; Division of Immunobiology and Center for Systems Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.
  • Martin LJ; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.
  • Witte D; Division of Pathology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.
  • Setchell KD; Laboratory of Mass Spectroscopy, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.
  • Mckay MA; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.
  • Magnusen AF; Division of Immunobiology and Center for Systems Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.
  • Zhang W; Laboratory of Mass Spectroscopy, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.
  • Liou B; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.
  • Köhl J; Division of Immunobiology and Center for Systems Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.
  • Grabowski GA; Institute for Systemic Inflammation Research, University of Lübeck, 23562 Lübeck, Germany.
Nature ; 543(7643): 108-112, 2017 03 02.
Article em En | MEDLINE | ID: mdl-28225753
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas do Sistema Complemento / Doença de Gaucher / Glucosilceramidas / Inflamação Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas do Sistema Complemento / Doença de Gaucher / Glucosilceramidas / Inflamação Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2017 Tipo de documento: Article