Compliments of Factor H: What's in it for AMD?
Immunity
; 46(2): 167-169, 2017 02 21.
Article
em En
| MEDLINE
| ID: mdl-28228273
ABSTRACT
Genetic variations in complement factor H (CFH) confer greater risk for age-related macular degeneration (AMD). In this issue of Immunity, Calippe et al. (2017) uncover a non-canonical role for CFH in the inhibition of mononuclear phagocyte elimination from sub-retinal lesions, providing insight into the pathophysiology of AMD associated with CFH variants.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Fator H do Complemento
/
Degeneração Macular
Limite:
Humans
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article