Ganglioglioma Arising From Desmoplastic Medulloblastoma: A Case Report and Review of Literature.
Pediatrics
; 139(3)2017 Mar.
Article
em En
| MEDLINE
| ID: mdl-28232638
ABSTRACT
We describe a case of medulloblastoma maturating into ganglioglioma during therapy. A 10-month-old boy was diagnosed with a desmoplastic medulloblastoma and was treated with gross total resection followed by induction chemotherapy. A recurrence in the tumor bed during therapy was managed with focal radiation therapy and consolidation chemotherapy. After further progression, the recurrent tumor was resected completely. The histopathology revealed a benign ganglioglioma with no residual medulloblastoma. This case raises the possibility that a malignant medulloblastoma can differentiate into a benign tumor and suggests that differentiation therapy may have value in the treatment of medulloblastoma.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Infratentoriais
/
Neoplasias Cerebelares
/
Segunda Neoplasia Primária
/
Ganglioglioma
/
Meduloblastoma
Limite:
Child
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article