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Mitochondrial DNA oxidation induces imbalanced activity of NLRP3/NLRP6 inflammasomes by activation of caspase-8 and BRCC36 in dry eye.
Chi, Wei; Hua, Xia; Chen, Xin; Bian, Fang; Yuan, Xiaoyong; Zhang, Lili; Wang, Xiaoran; Chen, Ding; Deng, Ruzhi; Li, Zhijie; Liu, Yizhi; de Paiva, Cintia S; Pflugfelder, Stephen C; Li, De-Quan.
Afiliação
  • Chi W; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China; Ocular Surface Center, Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA. Electronic address: chiwei@mail.sysu.edu.cn.
  • Hua X; Ocular Surface Center, Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA; Second Hospital of Tianjin Medical University, Tianjin, China. Electronic address: 849795145@qq.com.
  • Chen X; Ocular Surface Center, Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA; School of Optometry and Ophthalmology, Wenzhou Medical University, Wenzhou, China. Electronic address: Xin.Chen@bcm.edu.
  • Bian F; Ocular Surface Center, Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA. Electronic address: Fang.Bian@bcm.edu.
  • Yuan X; Ocular Surface Center, Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA. Electronic address: yuanxy_cn@hotmail.com.
  • Zhang L; Ocular Surface Center, Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA.
  • Wang X; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China; Ocular Surface Center, Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA. Electronic address: Xiaoran.Wang@bcm.edu.
  • Chen D; Ocular Surface Center, Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA; School of Optometry and Ophthalmology, Wenzhou Medical University, Wenzhou, China. Electronic address: Ding.Chen@bcm.edu.
  • Deng R; Ocular Surface Center, Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA; School of Optometry and Ophthalmology, Wenzhou Medical University, Wenzhou, China. Electronic address: 2335281147@qq.com.
  • Li Z; Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA. Electronic address: zhijiel@bcm.edu.
  • Liu Y; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China. Electronic address: yzliu62@yahoo.com.
  • de Paiva CS; Ocular Surface Center, Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA. Electronic address: cintiadp@bcm.edu.
  • Pflugfelder SC; Ocular Surface Center, Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA. Electronic address: stevenp@bcm.edu.
  • Li DQ; Ocular Surface Center, Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA. Electronic address: dequanl@bcm.edu.
J Autoimmun ; 80: 65-76, 2017 Jun.
Article em En | MEDLINE | ID: mdl-28238526
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA Mitocondrial / Síndromes do Olho Seco / Epitélio Corneano / Caspase 8 / Inflamassomos / Proteínas de Membrana Limite: Adolescent / Adult / Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA Mitocondrial / Síndromes do Olho Seco / Epitélio Corneano / Caspase 8 / Inflamassomos / Proteínas de Membrana Limite: Adolescent / Adult / Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article