Mediator structure and rearrangements required for holoenzyme formation.

Tsai, Kuang-Lei; Yu, Xiaodi; Gopalan, Sneha; Chao, Ti-Chun; Zhang, Ying; Florens, Laurence; Washburn, Michael P; Murakami, Kenji; Conaway, Ronald C; Conaway, Joan W; Asturias, Francisco J

Tsai, Kuang-Lei; Yu, Xiaodi; Gopalan, Sneha; Chao, Ti-Chun; Zhang, Ying; Florens, Laurence; Washburn, Michael P; Murakami, Kenji; Conaway, Ronald C; Conaway, Joan W; Asturias, Francisco J.

Afiliação

Tsai KL; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla California, USA.
Yu X; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla California, USA.
Gopalan S; Stowers Institute for Medical Research, Kansas City, Missouri, USA.
Chao TC; Department of Pediatrics and Institute for Genomic Medicine, University of California San Diego School of Medicine, La Jolla, California, USA.
Zhang Y; Stowers Institute for Medical Research, Kansas City, Missouri, USA.
Florens L; Stowers Institute for Medical Research, Kansas City, Missouri, USA.
Washburn MP; Stowers Institute for Medical Research, Kansas City, Missouri, USA.
Murakami K; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City Kansas, USA.
Conaway RC; Department of Structural Biology, Stanford University School of Medicine, Stanford, California, USA.
Conaway JW; Stowers Institute for Medical Research, Kansas City, Missouri, USA.
Asturias FJ; Department of Biochemistry &Molecular Biology, University of Kansas Medical Center, Kansas City, Kansas, USA.

Nature ; 544(7649): 196-201, 2017 04 13.

Article em En | MEDLINE | ID: mdl-28241144

Assuntos

Complexo Mediador/química; Complexo Mediador/metabolismo; RNA Polimerase II/química; RNA Polimerase II/ultraestrutura; Sítios de Ligação; Microscopia Crioeletrônica; Holoenzimas/química; Holoenzimas/metabolismo; Holoenzimas/ultraestrutura; Complexo Mediador/ultraestrutura; Modelos Moleculares; Ligação Proteica; Conformação Proteica; Subunidades Proteicas/química; Subunidades Proteicas/metabolismo; RNA Polimerase II/metabolismo; Schizosaccharomyces; Proteínas de Schizosaccharomyces pombe/química; Proteínas de Schizosaccharomyces pombe/metabolismo; Proteínas de Schizosaccharomyces pombe/ultraestrutura; Relação Estrutura-Atividade

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: RNA Polimerase II / Complexo Mediador Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: RNA Polimerase II / Complexo Mediador Idioma: En Ano de publicação: 2017 Tipo de documento: Article