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Using Factor Mixture Models to Evaluate the Type A/B Classification of Alcohol Use Disorders in a Heterogeneous Treatment Sample.
Hildebrandt, Tom; Epstein, Elizabeth E; Sysko, Robyn; Bux, Donald A.
Afiliação
  • Hildebrandt T; Department of Psychiatry, Mount Sinai School of Medicine, New York, New York.
  • Epstein EE; Center of Alcohol Studies, Rutgers - The State University of New Jersey, Piscataway, New Jersey.
  • Sysko R; Department of Psychiatry, University of Massachusetts Medical School, Worcester, Massachusetts.
  • Bux DA; Department of Psychiatry, Mount Sinai School of Medicine, New York, New York.
Alcohol Clin Exp Res ; 41(5): 987-997, 2017 May.
Article em En | MEDLINE | ID: mdl-28247423
ABSTRACT

BACKGROUND:

The type A/B classification model for alcohol use disorders (AUDs) has received considerable empirical support. However, few studies examine the underlying latent structure of this subtyping model, which has been challenged as a dichotomization of a single drinking severity dimension. Type B, relative to type A, alcoholics represent those with early age of onset, greater familial risk, and worse outcomes from alcohol use.

METHODS:

We examined the latent structure of the type A/B model using categorical, dimensional, and factor mixture models in a mixed-gender community treatment-seeking sample of adults with an AUD.

RESULTS:

Factor analytic models identified 2 factors (drinking severity/externalizing psychopathology and internalizing psychopathology) underlying the type A/B indicators. A factor mixture model with 2 dimensions and 3 classes emerged as the best overall fitting model. The classes reflected a type A class and 2 type B classes (B1 and B2) that differed on the respective level of drinking severity/externalizing pathology and internalizing pathology. Type B1 had a greater prevalence of women and more internalizing pathology and B2 had a greater prevalence of men and more drinking severity/externalizing pathology. The 2-factor, 3-class model also exhibited predictive validity by explaining significant variance in 12-month drinking and drug use outcomes.

CONCLUSIONS:

The model identified in this study may provide a basis for examining different sources of heterogeneity in the course and outcome of AUDs.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Alcoolismo / Modelos Psicológicos Tipo de estudo: Etiology_studies / Evaluation_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Alcoolismo / Modelos Psicológicos Tipo de estudo: Etiology_studies / Evaluation_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article