Cytotoxicity of Natural Killer Cells Activated Through NKG2D Contributes to the Development of Bronchiolitis Obliterans in a Murine Heterotopic Tracheal Transplant Model.

Kawakami, T; Ito, K; Matsuda, Y; Noda, M; Sakurada, A; Hoshikawa, Y; Okada, Y; Ogasawara, K

Kawakami, T; Ito, K; Matsuda, Y; Noda, M; Sakurada, A; Hoshikawa, Y; Okada, Y; Ogasawara, K.

Afiliação

Kawakami T; Department of Immunobiology, Institute of Development, Aging and Cancer, Tohoku University, Aoba-ku, Sendai, Miyagi, Japan.
Ito K; Department of Thoracic Surgery, Graduate School of Medicine, Tohoku University, Aoba-ku, Sendai, Miyagi, Japan.
Matsuda Y; Department of Immunobiology, Institute of Development, Aging and Cancer, Tohoku University, Aoba-ku, Sendai, Miyagi, Japan.
Noda M; Department of Thoracic Surgery, Graduate School of Medicine, Tohoku University, Aoba-ku, Sendai, Miyagi, Japan.
Sakurada A; Department of Thoracic Surgery, Graduate School of Medicine, Tohoku University, Aoba-ku, Sendai, Miyagi, Japan.
Hoshikawa Y; Department of Thoracic Surgery, Graduate School of Medicine, Tohoku University, Aoba-ku, Sendai, Miyagi, Japan.
Okada Y; Department of Thoracic Surgery, Graduate School of Medicine, Fujita Health University, Toyoake, Aichi, Japan.
Ogasawara K; Department of Thoracic Surgery, Graduate School of Medicine, Tohoku University, Aoba-ku, Sendai, Miyagi, Japan.

Am J Transplant ; 17(9): 2338-2349, 2017 Sep.

Article em En | MEDLINE | ID: mdl-28251796

Assuntos

Bronquiolite Obliterante/etiologia; Modelos Animais de Doenças; Rejeição de Enxerto/etiologia; Células Matadoras Naturais/patologia; Subfamília K de Receptores Semelhantes a Lectina de Células NK/metabolismo; Traqueia/transplante; Transplante Heterotópico/efeitos adversos; Animais; Bronquiolite Obliterante/metabolismo; Bronquiolite Obliterante/patologia; Linfócitos T CD8-Positivos/imunologia; Células Cultivadas; Rejeição de Enxerto/metabolismo; Rejeição de Enxerto/patologia; Proteínas de Homeodomínio/fisiologia; Imunidade Celular; Células Matadoras Naturais/imunologia; Células Matadoras Naturais/metabolismo; Camundongos; Camundongos Endogâmicos BALB C; Camundongos Endogâmicos C57BL; Camundongos SCID

Palavras-chave

basic (laboratory) research/science; bronchiolitis obliterans (BOS); lung transplantation/pulmonology; natural killer (NK) cells/NK receptors

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Traqueia / Bronquiolite Obliterante / Células Matadoras Naturais / Transplante Heterotópico / Modelos Animais de Doenças / Subfamília K de Receptores Semelhantes a Lectina de Células NK / Rejeição de Enxerto Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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