SIDT2 mediates gymnosis, the uptake of naked single-stranded oligonucleotides into living cells.

Takahashi, Masayuki; Contu, Viorica Raluca; Kabuta, Chihana; Hase, Katsunori; Fujiwara, Yuuki; Wada, Keiji; Kabuta, Tomohiro

SIDT2 mediates gymnosis, the uptake of naked single-stranded oligonucleotides into living cells.

Takahashi, Masayuki; Contu, Viorica Raluca; Kabuta, Chihana; Hase, Katsunori; Fujiwara, Yuuki; Wada, Keiji; Kabuta, Tomohiro.

Afiliação

Takahashi M; a Department of Degenerative Neurological Diseases , National Institute of Neuroscience, National Center of Neurology and Psychiatry , Kodaira, Tokyo , Japan.
Contu VR; a Department of Degenerative Neurological Diseases , National Institute of Neuroscience, National Center of Neurology and Psychiatry , Kodaira, Tokyo , Japan.
Kabuta C; b Department of Neurology, Interdisciplinary Graduate School of Medicine and Engineering , University of Yamanashi , Yamanashi , Japan.
Hase K; a Department of Degenerative Neurological Diseases , National Institute of Neuroscience, National Center of Neurology and Psychiatry , Kodaira, Tokyo , Japan.
Fujiwara Y; a Department of Degenerative Neurological Diseases , National Institute of Neuroscience, National Center of Neurology and Psychiatry , Kodaira, Tokyo , Japan.
Wada K; a Department of Degenerative Neurological Diseases , National Institute of Neuroscience, National Center of Neurology and Psychiatry , Kodaira, Tokyo , Japan.
Kabuta T; a Department of Degenerative Neurological Diseases , National Institute of Neuroscience, National Center of Neurology and Psychiatry , Kodaira, Tokyo , Japan.

RNA Biol ; 14(11): 1534-1543, 2017 11 02.

Article em En | MEDLINE | ID: mdl-28277980

Assuntos

MicroRNAs/antagonistas & inibidores; Proteínas de Transporte de Nucleotídeos/genética; Oligonucleotídeos Antissenso/genética; Interferência de RNA; Animais; Linhagem Celular; Fibroblastos/citologia; Fibroblastos/metabolismo; Corantes Fluorescentes/química; Expressão Gênica; Células HeLa; Compostos Heterocíclicos de 4 ou mais Anéis/química; Humanos; Camundongos; MicroRNAs/genética; MicroRNAs/metabolismo; Mutação; Proteínas de Transporte de Nucleotídeos/metabolismo; Oligonucleotídeos Antissenso/metabolismo; Plasmídeos/química; Plasmídeos/metabolismo; Transporte de RNA; Rodaminas/metabolismo; Coloração e Rotulagem/métodos

Palavras-chave

Gymnosis; RNA channel; SIDT2; membrane protein; single-stranded oligonucleotides

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oligonucleotídeos Antissenso / Proteínas de Transporte de Nucleotídeos / MicroRNAs / Interferência de RNA Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google