[Advances in clinical research on rtA181 mutation in hepatitis B virus].
Zhonghua Gan Zang Bing Za Zhi
; 25(1): 69-72, 2017 Jan 20.
Article
em Zh
| MEDLINE
| ID: mdl-28297788
ABSTRACT
Nowadays, nucleos(t)ide analogues (NAs) are important drugs for the treatment of chronic hepatitis B and can suppress the virus through inhibiting the activity of hepatitis B virus (HBV) polymerase. However, rtA181 mutation in HBV can reduce the sensitivity of HBV to various NAs, which brings new challenges to antiviral therapy. This article briefly introduces the research advances in the clinical detection rate of rtA181 mutation and its influence on therapeutic effect and prognosis.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Antivirais
/
Vírus da Hepatite B
/
Mutação Puntual
/
Hepatite B Crônica
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
Zh
Ano de publicação:
2017
Tipo de documento:
Article