Chronic granulomatous disease as a risk factor for cutaneous lupus in childhood.
Dermatol Online J
; 23(3)2017 Mar 15.
Article
em En
| MEDLINE
| ID: mdl-28329526
ABSTRACT
Chronic granulomatous disease (CGD) is a primaryimmunodeficiency disorder that affects the phagocyticcells of the innate immune system. It is characterizedby recurrent or persistent infections with granulomaformation. Lupus-like lesions have been reported incarriers of CGD and less frequently, in patients withCGD. Immunological study in these patients areusually negative. We describe the case of an 8-yearoldboy with CGD who developed chronic and acutecutaneous lupus erythematous with angular cheilitis,oral ulcers, Raynaud phenomenon, and positiveserologies for antinuclear, anticentromere, and anti-Saccharomyces cerevisiae antibodies.
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Base de dados:
MEDLINE
Assunto principal:
Lúpus Eritematoso Cutâneo
/
Dermatoses Faciais
/
Dermatoses do Pé
/
Doença Granulomatosa Crônica
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Risk_factors_studies
Limite:
Child
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article