Haemophagocytic lymphohistiocytosis associated with fulminant hepatitis and multiorgan failure following primary Epstein-Barr virus and herpes simplex virus type 1 infection.
BMJ Case Rep
; 20172017 Mar 29.
Article
em En
| MEDLINE
| ID: mdl-28356254
ABSTRACT
We present a case of severe fatal hepatitis in a young patient presumably triggered by two ubiquitous viral diseases which occurred in close succession. This case is unusual because of the exceptional chronological sequence of primary Epstein-Barr virus and herpes simplex virus type 1 infection causing systemic immune dysregulation associated with rapidly developing liver failure and consecutive multiorgan failure. Clinical, laboratory and histopathological findings indicated the development of secondary haemophagocytic lymphohistiocytosis triggered by these closely succeeding viral primary infections.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Falência Hepática Aguda
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Infecções por Vírus Epstein-Barr
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Linfo-Histiocitose Hemofagocítica
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Herpes Simples
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Insuficiência de Múltiplos Órgãos
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
Limite:
Adult
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Humans
/
Male
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article