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Enhancer-Derived lncRNAs Regulate Genome Architecture: Fact or Fiction?
Fanucchi, Stephanie; Mhlanga, Musa M.
Afiliação
  • Fanucchi S; Division of Chemical, Systems, and Synthetic Biology, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa; Gene Expression and Biophysics Group, Biomedical Translational Research Initiative (BTRI), Council for Scientific and Industrial Research (CSIR) Biosciences, Pretoria, South Africa. Electronic address: parrucchiere@mhlangalab.org.
  • Mhlanga MM; Division of Chemical, Systems, and Synthetic Biology, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa; Gene Expression and Biophysics Group, Biomedical Translational Research Initiative (BTRI), Council for Scientific and Industrial Research (CSIR) Biosciences, Pretoria, South Africa. Electronic address: yoda@mhlangalab.org.
Trends Genet ; 33(6): 375-377, 2017 06.
Article em En | MEDLINE | ID: mdl-28359583
How does the non-coding portion of the genome contribute to the regulation of genome architecture? A recent paper by Tan et al. focuses on the relationship between cis-acting complex-trait-associated lincRNAs and the formation of chromosomal contacts in topologically associating domains (TADs).
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cromossomos / Elementos Facilitadores Genéticos / RNA Longo não Codificante Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cromossomos / Elementos Facilitadores Genéticos / RNA Longo não Codificante Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article