Cpipe: a comprehensive computational platform for sequence and structure-based analyses of Cysteine residues.

ABSTRACT

SUMMARY: Due to their chemical plasticity, Cysteine residues (Cys) can serve many different functions. Identification and classification of reactive Cys isn't a trivial job currently, no available tool exists for an all-round, comprehensive (inclusive of all different functional types) analysis of Cys; herein we present a computational platform called Cp i pe, dedicated to this task it implements state-of-the art protocols, elaborating and displaying a wealth of information, sufficiently orthogonal to allow a thorough evaluation of all major aspects of Cys reactivity. AVAILABILITY AND IMPLEMENTATION Cp i pe is implemented in Python and freely available at http//cpipe.explora-biotech.com/cpipe/start.py . All major browsers are supported. CONTACT s.marino@explora-biotech.com. SUPPLEMENTARY INFORMATION Supplementary data are available at Bioinformatics online.