Long non-coding RNA PVT1 promote LPS-induced septic acute kidney injury by regulating TNF&#945; and JNK/NF-&#954;B pathways in HK-2 cells.

Huang, Wei; Lan, Xiuwen; Li, Xueting; Wang, Dawei; Sun, Yinghao; Wang, Qian; Gao, Hong; Yu, Kaijiang

Long non-coding RNA PVT1 promote LPS-induced septic acute kidney injury by regulating TNFα and JNK/NF-κB pathways in HK-2 cells.

Huang, Wei; Lan, Xiuwen; Li, Xueting; Wang, Dawei; Sun, Yinghao; Wang, Qian; Gao, Hong; Yu, Kaijiang.

Afiliação

Huang W; Department of Intensive Care Unit, The Affiliated Tumor Hospital of Harbin Medical University, Harbin, Heilongjiang 150081, China.
Lan X; Department of Intensive Care Unit, The Affiliated Tumor Hospital of Harbin Medical University, Harbin, Heilongjiang 150081, China.
Li X; Department of Intensive Care Unit, The Affiliated Tumor Hospital of Harbin Medical University, Harbin, Heilongjiang 150081, China.
Wang D; Department of Intensive Care Unit, The Affiliated Tumor Hospital of Harbin Medical University, Harbin, Heilongjiang 150081, China.
Sun Y; Department of Intensive Care Unit, The Affiliated Tumor Hospital of Harbin Medical University, Harbin, Heilongjiang 150081, China.
Wang Q; Department of Intensive Care Unit, The Affiliated Tumor Hospital of Harbin Medical University, Harbin, Heilongjiang 150081, China.
Gao H; Department of Intensive Care Unit, The Affiliated Tumor Hospital of Harbin Medical University, Harbin, Heilongjiang 150081, China.
Yu K; Department of Intensive Care Unit, The Affiliated Tumor Hospital of Harbin Medical University, Harbin, Heilongjiang 150081, China. Electronic address: shuiqinghu11@126.com.

Int Immunopharmacol ; 47: 134-140, 2017 Jun.

Article em En | MEDLINE | ID: mdl-28391160

Assuntos

Injúria Renal Aguda/imunologia; Células Epiteliais/fisiologia; Rim/patologia; RNA Longo não Codificante/genética; Sepse/imunologia; Injúria Renal Aguda/induzido quimicamente; Injúria Renal Aguda/genética; Células Cultivadas; Humanos; Imunomodulação/genética; Inflamação; Interleucina-1beta/metabolismo; Interleucina-6/metabolismo; Lipopolissacarídeos/imunologia; MAP Quinase Quinase 4/metabolismo; NF-kappa B/metabolismo; RNA Longo não Codificante/imunologia; RNA Interferente Pequeno/genética; Sepse/induzido quimicamente; Sepse/genética; Transdução de Sinais; Fator de Necrose Tumoral alfa/metabolismo

Palavras-chave

Inflammatory response; JNK/NF-κB signaling pathway; Plasmacytoma variant translocation 1; Septic acute kidney injury

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sepse / Células Epiteliais / Injúria Renal Aguda / RNA Longo não Codificante / Rim Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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