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Group 6 Layered Transition-Metal Dichalcogenides in Lab-on-a-Chip Devices: 1T-Phase WS2 for Microfluidics Non-Enzymatic Detection of Hydrogen Peroxide.
Toh, Rou Jun; Mayorga-Martinez, Carmen C; Han, Jongyoon; Sofer, Zdenek; Pumera, Martin.
Afiliação
  • Toh RJ; Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Science, Nanyang Technological University , 637371 Singapore.
  • Mayorga-Martinez CC; BioSystems & Micromechanics IRG (BioSyM), Singapore-MIT Alliance for Research and Technology (SMART) Centre, S16-05-08, 3 Science Drive 2, 117543 Singapore.
  • Han J; Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Science, Nanyang Technological University , 637371 Singapore.
  • Sofer Z; BioSystems & Micromechanics IRG (BioSyM), Singapore-MIT Alliance for Research and Technology (SMART) Centre, S16-05-08, 3 Science Drive 2, 117543 Singapore.
  • Pumera M; Department of Electrical Engineering and Computer Science, Department of Biological Engineering, Massachusetts Institute of Technology , Cambridge, Massachusetts 02139, United States.
Anal Chem ; 89(9): 4978-4985, 2017 05 02.
Article em En | MEDLINE | ID: mdl-28394576
Two-dimensional (2D) layered transition-metal dichalcogenides (TMDs) have been placed in the spotlight for their advantageous properties for catalytic and sensing applications. However, little work is done to explore and exploit them in enhancing the performance of analytical lab-on-a-chip (LOC) devices. In this work, we demonstrate a simple, sensitive, and low-cost fabrication of electrochemical LOC microfluidic devices to be used for enzymatic detection. We integrated four t-BuLi exfoliated, group 6 TMD materials (MoS2, MoSe2, WS2, and WSe2) within the LOC devices by the drop-casting method and compared their performance for H2O2 detection. The 1T-phase WS2-based LOC device outperformed the rest of the TMD materials and exhibited a wide range of linear response (20 nM to 20 µM and 100 µM to 2 mM), low detection limit (2.0 nM), and good selectivity for applications in real sample analysis. This work may facilitate the expanded use of electrochemical LOC microfluidics, with its easier integrability, for applications in the field of biodiagnostics and sensing.

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies Idioma: En Ano de publicação: 2017 Tipo de documento: Article