Proteomics and irritable bowel syndrome.
Expert Rev Proteomics
; 14(5): 461-468, 2017 05.
Article
em En
| MEDLINE
| ID: mdl-28395553
INTRODUCTION: Irritable bowel syndrome (IBS) is a gastrointestinal disease that according to Rome IV criteria is subdivided into four subtypes. The pathophysiology of this disease is not well understood due to numerous factors playing multiple roles in disease development, such as diet, stress and hormones. IBS has a variety of symptoms and overlaps with many other gastrointestinal and non-gastrointestinal diseases. Area covered: This review aims to present an overview of implementation of proteomics in experimental studies in the field of IBS. Expert commentary: Proteomics is commonly used for biomarker discovery in and has also been extensively used in IBS research. The necessity of a sensitive and specific biomarker for IBS is apparent, but despite the intensive research performed in this field, an appropriate biomarker is not yet available.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Proteoma
/
Técnicas de Diagnóstico Molecular
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Proteômica
/
Síndrome do Intestino Irritável
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article