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Practical application of 3-substituted-2,6-difluoropyridines in drug discovery: Facile synthesis of novel protein kinase C theta inhibitors.
Katoh, Taisuke; Tomata, Yoshihide; Setoh, Masaki; Sasaki, Satoshi; Takai, Takafumi; Yoshitomi, Yayoi; Yukawa, Tomoya; Nakagawa, Hideyuki; Fukumoto, Shoji; Tsukamoto, Tetsuya; Nakada, Yoshihisa.
Afiliação
  • Katoh T; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Ltd, 26-1, Muraokahigashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan. Electronic address: taisuke.katoh@takeda.com.
  • Tomata Y; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Ltd, 26-1, Muraokahigashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Setoh M; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Ltd, 26-1, Muraokahigashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Sasaki S; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Ltd, 26-1, Muraokahigashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Takai T; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Ltd, 26-1, Muraokahigashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Yoshitomi Y; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Ltd, 26-1, Muraokahigashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Yukawa T; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Ltd, 26-1, Muraokahigashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Nakagawa H; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Ltd, 26-1, Muraokahigashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Fukumoto S; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Ltd, 26-1, Muraokahigashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Tsukamoto T; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Ltd, 26-1, Muraokahigashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Nakada Y; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Ltd, 26-1, Muraokahigashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
Bioorg Med Chem Lett ; 27(11): 2497-2501, 2017 06 01.
Article em En | MEDLINE | ID: mdl-28400232
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piridinas / Proteína Quinase C / Inibidores de Proteínas Quinases / Isoenzimas Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piridinas / Proteína Quinase C / Inibidores de Proteínas Quinases / Isoenzimas Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article